April 18, 2014 1:46 pm
Cloning has finally generated immunologically compatible embryonic stem cells for older humans: two men aged 35 and 75. It may also generate significantly fewer tumor-causing mutations than the popular induced pluripotent stem cell (iPSC) method of making ES cells.
April 17, 2014 2:24 pm
Size doesn’t matter as long as long as you can get the job done. That said, one may be forgiven the impression that larger molecules—antibodies and related constructs, or T cells themselves being used in immunotherapies—were preferentially presented at American Association of Cancer Research annual conference
April 16, 2014 2:05 pm
The potential of immunotherapies drew large interest at this year's American Association for Cancer Research annual meeting. And the new data are particularly striking for their clinical results—reporting once uncommon at this basic research meeting.
April 3, 2014 2:16 pm
In successful research, any one path can quickly lead to new paths of even more promising results. This branching out of a research project couldn’t be more true than for a team of researchers at the UCSD’s Jacobs School of Engineering. UCSD researchers have developed “nanosponges” that were initially designed as a platform for cancer drug delivery and now are being developed to soak up the dangerous pore-forming toxin produced by MRSA.
April 1, 2014 4:10 pm
Riken Institute brass want co-authors of the “acid bath” stem cell papers to retract one, after appeal, citing two instances of deliberate misconduct. But two developments may delay this. First, lead author Haruko Obokata refuses to accept it. Second, Kenneth Lee became the first scientist outside the co-authors to publicly claim that, following the latest revised protocol for making acid bath cells, he has made them.
March 4, 2014 4:51 pm
At least two camps have formed in the “breast cancer stem cell” world. One camp believes most cancers may come from stem cells—or stem-like progenitors—gone awry. Others agree cancers can be most virulent when reaching a stem cell-like state—but believe they may come from both stem cells and mature cells gone awry.
February 24, 2014 2:41 pm
Cardiac arrhythmia is one of the most common diseases encountered in clinical cardiology. High-speed electrophysiological imaging using fluorescent probes has yielded tremendous insights into the basic mechanisms of arrhythmias and the effects of anti-arrhythmic drugs. However, optical mapping, as it is known to the cardiac research community, has remained relegated to the isolated (i.e. explanted) heart.
February 20, 2014 2:19 pm
Researchers have another answer to the question of how females can generate so much blood—blood enough for two blood systems—during pregnancy. The answer is stem cells, as is so often the case lately when a question has something to do with underlying biological mechanisms, is.