Recent Articles

August 27, 2014 9:58 am
Seth Lederman, M.D., CEO, Tonix Pharmaceuticals
Drugs can be discovered and developed in two very different ways: at an evolutionary pace and at a revolutionary pace. The “first revolution” in biological psychiatry took place in the 1950s, and now, in the 21st century, a “second revolution” of drug development and discovery is taking place, driven by repurposing.
August 26, 2014 11:31 am
Cynthia Fox, Science Editor
An experimental drug saved the lives of 16 of 16 monkeys with the Marburg virus, a killer near-indistinguishable from Ebola, just as symptoms broke out, said a new study. Read more...                   
August 25, 2014 9:49 am
Cynthia Fox, Science Editor
The birth control pill significantly affects ovarian reserve— or the number of immature eggs in a woman’s ovaries— which can be a predictor of future fertility, according to a team in Denmark. Read more...             
August 22, 2014 10:34 am
By Louise Rozik, Editor
Neglected by the pharmaceutical industry before the Orphan Drug Act of 1983, rare diseases are now front and center in pharma R&D, with approximately one-third of all new medicines approved by the FDA in the past 5 years were developed for the treatment of diseases that affect fewer than 200,000 Americans. Read more...
August 21, 2014 3:02 pm
Cynthia Fox, Science Writer
As, all around them, everyone from Derek Jeter to the Kennedy family was dousing themselves in ice water for the ALS “Ice Bucket Challenge,” Harvard researchers announced last week they may have found an ALS therapy. Read more...      
August 20, 2014 11:10 am
Chris Plaford, CFA, Chief Executive Officer, Claravant Analytics LLC
According to industry estimates, the majority of drugs in development will never make it to FDA approval. While a lack of efficacy is often a key factor, many clinical programs are derailed due to avoidable setbacks that can cause delays and significantly increase costs. Read more...
August 19, 2014 11:23 am
Sharon Benzeno, PhD, MBA, Senior Director, Business Development Bioinformatics, Elsevier
Big data is one of the hottest topics in R&D as its potential to accelerate successful drug development becomes more widely recognized. Part 2 of this two-part article analyses the new data-driven decision-making approaches make a difference to life science R&D. Read more...
August 18, 2014 3:14 pm
Cynthia Fox, Science Editor
A scientist has found that a compound, LY-411575, can restore 20% of hearing in deaf mice, or ten decibels. Since electroacoustic hearing aids, at best, improve hearing by five decibels, there is a “good chance” the work will lead to help for deafened patients.
August 15, 2014 9:09 am
Sharon Benzeno, PhD, MBA, Senior Director, Business Development Bioinformatics, Elsevier
Big data promises big insights for drug discovery and development, but its intrinsic value will be unlocked only if R&D organizations have the tools to make sense of it. Part 1 of this two-part article looks at how new models are changing the world of R&D. Read more...
July 31, 2014 1:21 pm
Louise Rozik, Editor
Scientists are accustomed to the fickle nature of research, but sometimes it can get to even the most seasoned researcher. One especially poignant example – the Cancer Genome Atlas – starts with the completion of the Human Genome Project in 2003. Read more...
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