Recent Articles

November 24, 2015 9:22 am
Cynthia Fox, Science Writer
 For an intense global program called 1000 Girls-1000 Futures, the NYAS recently sought 60 women willing to devote a full year to mentees from Mexico alone. NYAS head Ellis Rubenstein told the presser Mexican supporters were “terrified” no one would step up. But 170 woman researchers—and counting— stepped up worldwide.  
November 19, 2015 8:56 am
Bevin Fletcher, Associate Editor
Lyophilization, also known as freeze-drying, is a critical technology for the food industry, pharmaceuticals and biotech. However, the process, which removes water from products at low temperatures and low pressure, is expensive, time-consuming and has remained unchanged for the last 50 years. 
November 6, 2015 8:38 am
Qian Shi, Ph.D., Executive Director of Cancer Pharmacology, Crown Bioscience
There is a great unmet need for improved preclinical models, with functional immunity, to drive forward promising immunotherapy research in oncology and to enable the successful transition of immunotherapeutics from the laboratory to the clinic. The benefits these models can provide could drive the development of combination therapy, improving patient comfort and saving lives.
November 5, 2015 8:59 am
Rishi Porecha, Ph.D.
ELISA – Enzyme-Linked Immunosorbent Assay – is a commonly used biochemical technique for the evaluation of an antigen or antibody in a sample. This technique is used in a wide range of applications, including: clinical diagnostics, plant pathology, the detection of food allergens and drug screening.
November 4, 2015 9:01 am
Cynthia Fox, Science Writer
Early metastatic breast cancer cells are, strikingly, far more like stem cells than other tumor cells, says a new Nature study. They switch from a dormant (and unnoticed) stem cell-like state in primary tumors, to a more active, virulent state when kick-starting regression years later. The discovery could result in earlier detection of—and better drugs for—metastatic breast cancers.
November 4, 2015 9:02 am
Ivona Strug and Timothy Nadler, EMD Millipore Corporation
In this case study, we show how Trifluoroacetate (TFA) salts hamper peptide analysis by FTIR spectroscopy. Subsequently, we present a detailed method by which TFA can be exchanged for HCl, with the goal of increasing the reproducibility and accuracy of peptide-based assays.
October 28, 2015 8:44 am
Nancy Dreyer, MPH, Ph.D., Global Chief of Scientific Affairs and Michelle Leavy, MPH, Manager, Health Policy, Quintiles
Understanding drug safety is a tricky thing. The use of direct-to-patient (or consumer) registry data is a new approach, and one that is quite different from the highly controlled world of clinical trials. Some worry about whether patients will be accurate and honest reporters. Will these patients be reliable, and will they provide clinically generalizable information?
October 22, 2015 9:10 am
Cynthia Fox, Science Writer
Like a bad teenager, in 95 percent of all amyotrophic lateral sclerosis (ALS) cases, a protein called TDP-43 leaves its home— the nucleus of motor neuron cells—to congregate, in suspect fashion, in the cytoplasm. In a study published in Science this summer, the Johns Hopkins University (JHU) team of pathologist Phillip Wong, Ph.D., offered new insight into this molecular rebellion.
October 21, 2015 9:38 am
Cynthia Fox, Science Writer
Embryonic stem (ES) cell-like stem cells made from adult cells—and morphed into eye cells—are not rejected by the immune system, according to “humanized mouse” data in Cell Stem Cell.
October 14, 2015 8:56 am
Mary M. Murphy, Ph.D., Applications Scientist, Reichert Life Sciences
The technique of Surface Plasmon Resonance (SPR), allows scientists to monitor biomolecular binding interactions label-free, in real-time and using automation. For those of you thinking about, or planning on, using SPR, this article offers insights on how to use the technique successfully, gained from working with this technique for a number of years.
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